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G(i) proteins mediate activation of the canonical hedgehog pathway in the myocardium
During myocardial ischemia, upregulation of the hedgehog (Hh) pathway promotes neovascularization and increases cardiomyocyte survival. The canonical Hh pathway activates a transcriptional program through the Gli family of transcription factors by derepression of the seven-transmembrane protein smoo...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4080174/ https://ncbi.nlm.nih.gov/pubmed/24816261 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00166.2014 |
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