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Extreme HOT regions are CpG-dense promoters in C. elegans and humans
Most vertebrate promoters lie in unmethylated CpG-dense islands, whereas methylation of the more sparsely distributed CpGs in the remainder of the genome is thought to contribute to transcriptional repression. Nonmethylated CG dinucleotides are recognized by CXXC finger protein 1 (CXXC1, also known...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4079969/ https://ncbi.nlm.nih.gov/pubmed/24653213 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.161992.113 |
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