Reversible Suppression of Cyclooxygenase 2 (COX-2) Expression In Vivo by Inducible RNA Interference

Prostaglandin-endoperoxide synthase 2 (PTGS2), also known as cyclooxygenase 2 (COX-2), plays a critical role in many normal physiological functions and modulates a variety of pathological conditions. The ability to turn endogenous COX-2 on and off in a reversible fashion, at specific times and in sp...

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Main Authors: Zaiss, Anne K., Zuber, Johannes, Chu, Chun, Machado, Hidevaldo B., Jiao, Jing, Catapang, Arthur B., Ishikawa, Tomo-o, Gil, Jose S., Lowe, Scott W., Herschman, Harvey R.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4079684/
https://ncbi.nlm.nih.gov/pubmed/24988319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0101263
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