Melphalan Alone or Conjugated to a Follicle Stimulating Hormone-β Peptide Kills Murine Testicular Cells in vitro and Transiently Suppresses Murine Spermatogenesis in vivo

New approaches to sterilizing male animals are needed to control captive and wild animal populations. We sought to develop a non-surgical method of permanent sterilization for male animals by administering the gonadotoxicant melphalan conjugated to peptides derived from the β-chain of follicle stimu...

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Hlavní autoři: Amory, John K., Hong, SungWoo, Yu, Xiaozhong, Muller, Charles H., Faustman, Elaine, Goldstein, Alex
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4079550/
https://ncbi.nlm.nih.gov/pubmed/24746827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.theriogenology.2014.03.014
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