Identification of an additional gene required for eukaryotic nonsense mRNA turnover.
Loss of function of any one of three UPF genes prevents the accelerated decay of nonsense mRNAs in Saccharomyces cerevisiae. We report the identification and DNA sequence of UPF3, which is present in one nonessential copy on chromosome VII. Upf3 contains three putative nuclear localization signal se...
Gardado en:
| Publicado en: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
1995
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40795/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7479783/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.22.10354 |
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