Identification of an additional gene required for eukaryotic nonsense mRNA turnover.
Loss of function of any one of three UPF genes prevents the accelerated decay of nonsense mRNAs in Saccharomyces cerevisiae. We report the identification and DNA sequence of UPF3, which is present in one nonessential copy on chromosome VII. Upf3 contains three putative nuclear localization signal se...
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| Опубликовано в:: | Proc Natl Acad Sci U S A |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
1995
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40795/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7479783/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.22.10354 |
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