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Enhancement of Inhibitory Neurotransmission by GABA(A) Receptors Having α(2,3)-Subunits Ameliorates Behavioral Deficits in a Mouse Model of Autism
Autism spectrum disorder (ASD) may arise from increased ratio of excitatory to inhibitory neurotransmission in the brain. Many pharmacological treatments have been tested in ASD, but only limited success has been achieved. Here we report that BTBR T(+) Itpr3(tf)/J (BTBR) mice, a model of idiopathic...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4079471/ https://ncbi.nlm.nih.gov/pubmed/24656250 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2014.01.016 |
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