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The GABA(A) receptor β subunit is required for inhibitory transmission

While the canonical assembly of a GABA(A) receptor contains two α subunits, two β subunits, and a fifth subunit, it is unclear which variants of each subunit are necessary for native receptors. We used CRISPR/Cas9 to dissect the role of the GABA(A) receptor β subunits in inhibitory transmission onto...

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Detalhes bibliográficos
Publicado no:Neuron
Main Authors: Nguyen, Quynh-Anh, Nicoll, Roger A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6089239/
https://ncbi.nlm.nih.gov/pubmed/29706582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2018.03.046
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