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Biomechanics and Thermodynamics of Nanoparticle Interactions with Plasma and Endosomal Membrane Lipids in Cellular Uptake and Endosomal Escape

[Image: see text] To be effective for cytoplasmic delivery of therapeutics, nanoparticles (NPs) taken up via endocytic pathways must efficiently transport across the cell membrane and subsequently escape from the secondary endosomes. We hypothesized that the biomechanical and thermodynamic interacti...

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Autors principals: Peetla, Chiranjeevi, Jin, Shihua, Weimer, Jonathan, Elegbede, Adekunle, Labhasetwar, Vinod
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2014
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4079324/
https://ncbi.nlm.nih.gov/pubmed/24911361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/la5015219
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