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Biomechanics and Thermodynamics of Nanoparticle Interactions with Plasma and Endosomal Membrane Lipids in Cellular Uptake and Endosomal Escape

[Image: see text] To be effective for cytoplasmic delivery of therapeutics, nanoparticles (NPs) taken up via endocytic pathways must efficiently transport across the cell membrane and subsequently escape from the secondary endosomes. We hypothesized that the biomechanical and thermodynamic interacti...

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Detalhes bibliográficos
Main Authors: Peetla, Chiranjeevi, Jin, Shihua, Weimer, Jonathan, Elegbede, Adekunle, Labhasetwar, Vinod
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4079324/
https://ncbi.nlm.nih.gov/pubmed/24911361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/la5015219
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