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Selective biophysical interactions of surface modified nanoparticles with cancer cell lipids improve tumor targeting and gene therapy

Targeting gene- or drug-loaded nanoparticles (NPs) to tumors and ensuring their intratumoral retention after systemic administration remain key challenges to improving the efficacy of NP-based therapeutics. Here, we investigate a novel targeting approach that exploits changes in lipid metabolism and...

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書誌詳細
主要な著者: Sharma, Blanka, Peetla, Chiranjeevi, Adjei, Isaac M., Labhasetwar, Vinod
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3669664/
https://ncbi.nlm.nih.gov/pubmed/23523612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2013.03.011
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