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Selective biophysical interactions of surface modified nanoparticles with cancer cell lipids improve tumor targeting and gene therapy
Targeting gene- or drug-loaded nanoparticles (NPs) to tumors and ensuring their intratumoral retention after systemic administration remain key challenges to improving the efficacy of NP-based therapeutics. Here, we investigate a novel targeting approach that exploits changes in lipid metabolism and...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3669664/ https://ncbi.nlm.nih.gov/pubmed/23523612 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2013.03.011 |
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