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Detecting DNA Depurination with Solid-State Nanopores

Among the different types of DNA damage that occur endogenously in the cell, depurination is especially prevalent. These lesions can initiate mutagenesis and have been implicated in a variety of diseases, including cancer. Here, we demonstrate a new approach for the detection of depurination at the...

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Autori principali: Marshall, Michael M., Ruzicka, Jan A., Taylor, Ethan W., Hall, Adam R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4079296/
https://ncbi.nlm.nih.gov/pubmed/24988437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0101632
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