The molecular basis for apoptotic defects in patients with CD95 (Fas/Apo-1) mutations

Heterozygous mutations of the receptor CD95 (Fas/Apo-1) are associated with defective lymphocyte apoptosis and a clinical disease characterized by lymphadenopathy, splenomegaly, and systemic autoimmunity. From our cohort of 11 families, we studied eight patients to define the mechanisms responsible...

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Bibliografiske detaljer

Udgivet i:	J Clin Invest
Principais autores:	Vaishnaw, Akshay K., Orlinick, Jason R., Chu, Jia-Li, Krammer, Peter H., Chao, Moses V., Elkon, Keith B.
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Clinical Investigation 1999
Fag:	Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC407903/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9927496/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI5121
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