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Synaptic deficits in layer 5 neurons precede overt structural decay in 5xFAD mice
Synaptic decay and neurodegeneration are hallmarks of Alzheimer’s disease that are thought to precede dementia. Recently, we have reported that the first signs of neuritic dystrophy in a new transgenic mouse model of familial Alzheimer’s disease called the “5xFAD” are axonal dystrophy followed by lo...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4078998/ https://ncbi.nlm.nih.gov/pubmed/24055684 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2013.09.016 |
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