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Structural and mechanistic studies of polymerase η bypass of phenanthriplatin DNA damage
Platinum drugs are a mainstay of anticancer chemotherapy. Nevertheless, tumors often display inherent or acquired resistance to platinum-based treatments, prompting the search for new compounds that do not exhibit cross-resistance with current therapies. Phenanthriplatin, cis-diamminephenanthridinec...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2014
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4078841/ https://ncbi.nlm.nih.gov/pubmed/24927576 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1405739111 |
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