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Novel insight from transgenic mice into thyroid hormone resistance and the regulation of thyrotropin
Patients with resistance to thyroid hormone (RTH) exhibit elevated thyroid hormone levels and inappropriate thyrotropin (thyroid-stimulating hormone, or TSH) production. The molecular basis of this disorder resides in the dominant inhibition of endogenous thyroid hormone receptors (TRs) by a mutant...
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| Udgivet i: | J Clin Invest |
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| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical Investigation
1999
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC407884/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9916139/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI5205 |
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