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Taura syndrome virus IRES initiates translation by binding its tRNA-mRNA–like structural element in the ribosomal decoding center

In cap-dependent translation initiation, the open reading frame (ORF) of mRNA is established by the placement of the AUG start codon and initiator tRNA in the ribosomal peptidyl (P) site. Internal ribosome entry sites (IRESs) promote translation of mRNAs in a cap-independent manner. We report two st...

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Autors principals: Koh, Cha San, Brilot, Axel F., Grigorieff, Nikolaus, Korostelev, Andrei A.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4078839/
https://ncbi.nlm.nih.gov/pubmed/24927574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1406335111
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