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Taura syndrome virus IRES initiates translation by binding its tRNA-mRNA–like structural element in the ribosomal decoding center

In cap-dependent translation initiation, the open reading frame (ORF) of mRNA is established by the placement of the AUG start codon and initiator tRNA in the ribosomal peptidyl (P) site. Internal ribosome entry sites (IRESs) promote translation of mRNAs in a cap-independent manner. We report two st...

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Detalhes bibliográficos
Main Authors: Koh, Cha San, Brilot, Axel F., Grigorieff, Nikolaus, Korostelev, Andrei A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4078839/
https://ncbi.nlm.nih.gov/pubmed/24927574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1406335111
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