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The pulmonary circulation of homozygous or heterozygous eNOS-null mice is hyperresponsive to mild hypoxia

Acute hypoxic vasoconstriction and development of hypoxic pulmonary hypertension (PHTN) are unique properties of the pulmonary circulation. The pulmonary endothelium produces vasoactive factors, including nitric oxide (NO), that modify these phenomena. We tested the hypothesis that NO produced by en...

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Hlavní autoři: Fagan, Karen A., Fouty, Brian W., Tyler, Robert C., Morris, Kenneth G., Hepler, Lisa K., Sato, Koichi, LeCras, Timothy D., Abman, Steven H., Weinberger, Howard D., Huang, Paul L., McMurtry, Ivan F., Rodman, David M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 1999
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC407877/
https://ncbi.nlm.nih.gov/pubmed/9916141
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