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Aptamer-facilitated Protection of Oncolytic Virus from Neutralizing Antibodies

Oncolytic viruses promise to significantly improve current cancer treatments through their tumor-selective replication and multimodal attack against cancer cells. However, one of the biggest setbacks for oncolytic virus therapy is the intravenous delivery of the virus, as it can be cleared from the...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Muharemagic, Darija, Zamay, Anna, Ghobadloo, Shahrokh M, Evgin, Laura, Savitskaya, Anna, Bell, John C, Berezovski, Maxim V
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4078759/
https://ncbi.nlm.nih.gov/pubmed/24892725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2014.19
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