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Aptamer-Facilitated Cryoprotection of Viruses

[Image: see text] Global vaccination and gene therapy programs have an urgent demand for stabilization of viral vectors at low temperature. We used a quadramer, a bridge-connected DNA tetra-aptamer to antivesicular stomatitis virus (VSV), as a viral cryoprotectant. Results showed that the tetravalen...

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Bibliografske podrobnosti
izdano v:ACS Med Chem Lett
Main Authors: Ghobadloo, Shahrokh M., Gargaun, Ana, Casselman, Rebecca, Muharemagic, Darija, Berezovski, Maxim V.
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2014
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4233356/
https://ncbi.nlm.nih.gov/pubmed/25408838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml500322h
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