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Proof-of-principle that a decoy virus protects oncolytic measles virus against neutralizing antibodies
BACKGROUND: Attenuated oncolytic measles virus (OMV) is a promising antitumor agent in early-phase clinical trials. However, pre-existing immunity against measles might be a hurdle for OMV therapy. METHODS: OMV was inactivated with short-wavelength ultraviolet light (UV-C). Loss of replication and o...
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| Publicado no: | Oncolytic Virother |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove Medical Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5933358/ https://ncbi.nlm.nih.gov/pubmed/29750140 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OV.S150637 |
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