Mitophagy switches cell death from apoptosis to necrosis in NSCLC cells treated with oncolytic measles virus

Although apoptotic phenomena have been observed in malignant cells infected by measles virus vaccine strain Edmonston B (MV-Edm), the precise oncolytic mechanisms are poorly defined. In this study we found that MV-Edm induced autophagy and sequestosome 1-mediated mitophagy leading to decreased cytoc...

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Detalhes bibliográficos
Main Authors: Xia, Mao, Meng, Gang, Jiang, Aiqin, Chen, Aiping, Dahlhaus, Meike, Gonzalez, Patrick, Beltinger, Christian, Wei, Jiwu
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4116530/
https://ncbi.nlm.nih.gov/pubmed/25004098
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