Targeting of functional antibody-CD59 fusion proteins to a cell surface

Complement is involved in the pathogenesis of many diseases, and there is great interest in developing inhibitors of complement for therapeutic application. CD59 is a natural membrane-bound inhibitor of the cytolytic complement membrane attack complex (MAC). In this study, the preparation and charac...

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Veröffentlicht in:J Clin Invest
Hauptverfasser: Zhang, Hui-fen, Yu, Jinghua, Bajwa, Ednan, Morrison, Sherie L., Tomlinson, Stephen
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 1999
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Article
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC407863/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9884334/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI4607
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