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Binding of AID to DNA does not correlate with mutator activity
The DNA deaminase AID initiates somatic hypermutation (SHM) and class switch recombination (CSR) by deaminating cytidines to uridines at variable region (V) genes and switch (S) regions. The mechanism by which AID is recruited to V genes and S region DNA is poorly understood. Here we have employed t...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4078406/ https://ncbi.nlm.nih.gov/pubmed/24879790 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400433 |
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