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Detection of Gene Rearrangements in Targeted Clinical Next-Generation Sequencing

The identification of recurrent gene rearrangements in the clinical laboratory is the cornerstone for risk stratification and treatment decisions in many malignant tumors. Studies have reported that targeted next-generation sequencing assays have the potential to identify such rearrangements; howeve...

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Autors principals: Abel, Haley J., Al-Kateb, Hussam, Cottrell, Catherine E., Bredemeyer, Andrew J., Pritchard, Colin C., Grossmann, Allie H., Wallander, Michelle L., Pfeifer, John D., Lockwood, Christina M., Duncavage, Eric J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4078366/
https://ncbi.nlm.nih.gov/pubmed/24813172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmoldx.2014.03.006
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