Detection of Gene Rearrangements in Targeted Clinical Next-Generation Sequencing

The identification of recurrent gene rearrangements in the clinical laboratory is the cornerstone for risk stratification and treatment decisions in many malignant tumors. Studies have reported that targeted next-generation sequencing assays have the potential to identify such rearrangements; howeve...

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Main Authors: Abel, Haley J., Al-Kateb, Hussam, Cottrell, Catherine E., Bredemeyer, Andrew J., Pritchard, Colin C., Grossmann, Allie H., Wallander, Michelle L., Pfeifer, John D., Lockwood, Christina M., Duncavage, Eric J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Investigative Pathology 2014
Assuntos:
Regular Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4078366/
https://ncbi.nlm.nih.gov/pubmed/24813172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmoldx.2014.03.006
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