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Human telomerase catalyzes nucleolytic primer cleavage
Telomerase is a reverse transcriptase that uses an integral RNA molecule to add de novo G-rich repeats onto telomeric DNA, or onto nontelomeric DNA generated during chromosome fragmentation and breakage events. A telomerase-mediated DNA substrate cleavage activity has been reported in ciliates and y...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
2004
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC407828/ https://ncbi.nlm.nih.gov/pubmed/15096579 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh546 |
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