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Human telomerase catalyzes nucleolytic primer cleavage

Telomerase is a reverse transcriptase that uses an integral RNA molecule to add de novo G-rich repeats onto telomeric DNA, or onto nontelomeric DNA generated during chromosome fragmentation and breakage events. A telomerase-mediated DNA substrate cleavage activity has been reported in ciliates and y...

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Bibliografiske detaljer
Main Authors: Huard, Sylvain, Autexier, Chantal
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC407828/
https://ncbi.nlm.nih.gov/pubmed/15096579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh546
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