Abr and Bcr are multifunctional regulators of the Rho GTP-binding protein family.

Philadelphia chromosome-positive leukemias result from the fusion of the BCR and ABL genes, which generates a functional chimeric molecule. The Abr protein is very similar to Bcr but lacks a structural domain which may influence its biological regulatory capabilities. Both Abr and Bcr have a GTPase-...

Full description

Saved in:
Bibliographic Details
Main Authors: Chuang, T H, Xu, X, Kaartinen, V, Heisterkamp, N, Groffen, J, Bokoch, G M
Format: Artigo
Language:Inglês
Published: 1995
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC40780/
https://ncbi.nlm.nih.gov/pubmed/7479768
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items