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Abr and Bcr, Two Homologous Rac GTPase-Activating Proteins, Control Multiple Cellular Functions of Murine Macrophages

Small GTPases of the Rho family are key regulators of phagocytic leukocyte function. Abr and Bcr are homologous, multidomain proteins. Their C-terminal domain has GTPase-activating protein (GAP) activity that, in vitro, is specific for Rac and Cdc42. To address the in vivo relevance of these entire...

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Detalhes bibliográficos
Main Authors: Cho, Young Jin, Cunnick, Jess M., Yi, Sun-Ju, Kaartinen, Vesa, Groffen, John, Heisterkamp, Nora
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1800684/
https://ncbi.nlm.nih.gov/pubmed/17116687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00756-06
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