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Nanoparticle targeting to diseased vasculature for imaging and therapy

Significant challenges remain in targeting drugs to diseased vasculature; most important being rapid blood flow with high shear, limited availability of stable targets, and heterogeneity and recycling of cellular markers. We developed nanoparticles (NPs) to target degraded elastic lamina, a consiste...

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Detalhes bibliográficos
Main Authors: Sinha, Aditi, Shaporev, Aleksey, Nosoudi, Nasim, Lei, Yang, Vertegel, Alexey, Lessner, Susan, Vyavahare, Naren
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4077993/
https://ncbi.nlm.nih.gov/pubmed/24566276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2014.02.002
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