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Establishing 3-nitrotyrosine as a biomarker for the vasculopathy of Fabry disease
The endothelial dysfunction of Fabry disease results from α-galactosidase A deficiency leading to the accumulation of globotriaosylceramide. Vasculopathy in the α-galactosidase A null mouse is manifested as oxidant-induced thrombosis, accelerated atherogenesis, and impaired arterial reactivity. To b...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4077934/ https://ncbi.nlm.nih.gov/pubmed/24402087 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2013.520 |
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