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Differential involvement of COX1 and COX2 in the vasculopathy associated with the α-galactosidase A-knockout mouse
The lysosomal storage disorder Fabry disease is characterized by excessive globotriaosylceramide (Gb3) accumulation in major organs such as the heart and kidney. Defective lysosomal α-galactosidase A (Gla) is responsible for excessive Gb3 accumulation, and one cell sensitive to the effects of Gb3 ac...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2670691/ https://ncbi.nlm.nih.gov/pubmed/19202000 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00929.2008 |
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