Antitumor effect of iRGD-modified liposomes containing conjugated linoleic acid–paclitaxel (CLA-PTX) on B16-F10 melanoma

In the present study, we prepared a novel delivery system of iRGD (CRGDK/RGPD/EC)-modified sterically stabilized liposomes (SSLs) containing conjugated linoleic acid–paclitaxel (CLA-PTX). The anti-tumor effect of iRGD-SSL-CLA-PTX was investigated on B16-F10 melanoma in vitro and in vivo. The in vitr...

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Hlavní autoři: Du, Ruo, Zhong, Ting, Zhang, Wei-Qiang, Song, Ping, Song, Wen-Ding, Zhao, Yang, Wang, Chao, Tang, Yi-Qun, Zhang, Xuan, Zhang, Qiang
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2014
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4077607/
https://ncbi.nlm.nih.gov/pubmed/25028548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S65664
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