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Antitumor efficacy of a novel CLA-PTX microemulsion against brain tumors: in vitro and in vivo findings
BACKGROUND: Considering the observations that linoleic acid conjugated with paclitaxel (CLA-PTX) possesses antitumor activity against brain tumors, is able to cross the blood–brain barrier, but has poor water solubility, the purpose of this study was to prepare a novel CLA-PTX microemulsion and eval...
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| Main Authors: | , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove Medical Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3529648/ https://ncbi.nlm.nih.gov/pubmed/23269869 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S38927 |
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