Antitumor efficacy of a novel CLA-PTX microemulsion against brain tumors: in vitro and in vivo findings

BACKGROUND: Considering the observations that linoleic acid conjugated with paclitaxel (CLA-PTX) possesses antitumor activity against brain tumors, is able to cross the blood–brain barrier, but has poor water solubility, the purpose of this study was to prepare a novel CLA-PTX microemulsion and eval...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Li, Dan, Yang, Ke, Li, Jie-Si, Ke, Xi-Yu, Duan, Yu, Du, Ruo, Song, Ping, Yu, Ke-Fu, Ren, Wei, Huang, Dan, Li, Xing-Huo, Hu, Xin, Zhang, Xuan, Zhang, Qiang
Format: Artigo
Langue:Inglês
Publié: Dove Medical Press 2012
Sujets:
Original Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529648/
https://ncbi.nlm.nih.gov/pubmed/23269869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S38927
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