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Antitumor activity of dichloroacetate on C6 glioma cell: in vitro and in vivo evaluation
Dichloroacetate (DCA), a small molecule mitochondria-targeting agent, can penetrate the blood–brain barrier, showing potential therapeutic effects on brain tumors. Considering the effects of DCA on tumor cellular metabolism, penetrating across the blood–brain barrier, as well as having potential ant...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Dove Medical Press
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3601023/ https://ncbi.nlm.nih.gov/pubmed/23515860 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S40992 |
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