Antitumor activity of dichloroacetate on C6 glioma cell: in vitro and in vivo evaluation

Dichloroacetate (DCA), a small molecule mitochondria-targeting agent, can penetrate the blood–brain barrier, showing potential therapeutic effects on brain tumors. Considering the effects of DCA on tumor cellular metabolism, penetrating across the blood–brain barrier, as well as having potential ant...

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Main Authors: Duan, Yu, Zhao, Xin, Ren, Wei, Wang, Xin, Yu, Ke-Fu, Li, Dan, Zhang, Xuan, Zhang, Qiang
Formato: Artigo
Idioma:Inglês
Publicado: Dove Medical Press 2013
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Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3601023/
https://ncbi.nlm.nih.gov/pubmed/23515860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S40992
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