Inhibitory effect of Polo-like kinase 1 depletion on mitosis and apoptosis of gastric cancer cells

AIM: Polo-like kinase 1 (PLK1) serine/threonine kinase plays a vital role in multiple phases of mitosis in gastric cancer cells. To investigate the effect of PLK1 depletion on mitosis and apoptosis of gastric cancer cells. METHODS: PLK1 expression was blocked by small RNA interference(siRNA). The ex...

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Bibliografske podrobnosti
Main Authors: Chen, Xue-Hua, Lan, Bin, Qu, Ying, Zhang, Xiao-Qing, Cai, Qu, Liu, Bing-Ya, Zhu, Zheng-Gang
Format: Artigo
Jezik:Inglês
Izdano: Baishideng Publishing Group Co., Limited 2006
Teme:
Gastric Cancer
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4077490/
https://ncbi.nlm.nih.gov/pubmed/16440413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v12.i1.29
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