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Potential roles of Activation-Induced cytidine Deaminase in promotion or prevention of autoimmunity in humans

Autoimmune manifestations are paradoxical and frequent complications of primary immunodeficiencies, including T and/or B cell defects. Among pure B cell defects, the Activation-induced cytidine Deaminase (AID)-deficiency, characterized by a complete lack of immunoglobulin class switch recombination...

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Hlavní autoři: Durandy, Anne, Cantaert, Tineke, Kracker, Sven, Meffre, Eric
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4077434/
https://ncbi.nlm.nih.gov/pubmed/23215867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/08916934.2012.750299
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