Design, automated synthesis and immunological evaluation of NOD2-ligand–antigen conjugates

The covalent attachment of an innate immune system stimulating agent to an antigen can provide active vaccine modalities capable of eliciting a potent immune response against the incorporated antigen. Here we describe the design, automated synthesis and immunological evaluation of a set of four mura...

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Autors principals: Willems, Marian M J H P, Zom, Gijs G, Meeuwenoord, Nico, Ossendorp, Ferry A, Overkleeft, Herman S, van der Marel, Gijsbert A, Codée, Jeroen D C, Filippov, Dmitri V
Format: Artigo
Idioma:Inglês
Publicat: Beilstein-Institut 2014
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Full Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4077378/
https://ncbi.nlm.nih.gov/pubmed/24991299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.10.148
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