Laddar...

SOX2 hypomorphism disrupts development of the prechordal floor and optic cup

Haploinsufficiency for the HMG-box transcription factor SOX2 results in abnormalities of the human ventral forebrain and its derivative structures. These defects include anophthalmia (absence of eye), microphthalmia (small eye) and hypothalamic hamartoma (HH), an overgrowth of the ventral hypothalam...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Langer, Lee, Taranova, Olena, Sulik, Kathleen, Pevny, Larysa
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4077342/
https://ncbi.nlm.nih.gov/pubmed/22522080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mod.2012.04.001
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!