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Combinatorial regulation of optic cup progenitor cell fate by SOX2 and PAX6
In humans, haploinsufficiency of either SOX2 or PAX6 is associated with microphthalmia, anophthalmia or aniridia. In this study, through the genetic spatiotemporal specific ablation of SOX2 on both wild-type and Pax6-haploinsufficent backgrounds in the mouse, we have uncovered a transcriptionally di...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Company of Biologists
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3014633/ https://ncbi.nlm.nih.gov/pubmed/21205789 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.055178 |
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