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Positron Emission Tomography Imaging of Drug-Induced Tumor Apoptosis with a Caspase-Triggered Nano-aggregation Probe()
An (18)F-labeled caspase-3 sensitive nano-aggregation PET tracer ([(18)F]CSNAT) was prepared and evaluated for imaging caspase-3 activity in doxorubicin-treated tumor xenografts. This enzyme-activatable PET tracer is designed to function in a novel mechanism – enhanced retention of the (18)F activit...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4077287/ https://ncbi.nlm.nih.gov/pubmed/23881906 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201303422 |
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