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Rapamycin prevents the mutant huntingtin-suppressed GLT-1 expression in cultured astrocytes
AIM: To investigate the effects of rapamycin on glutamate uptake in cultured rat astrocytes expressing N-terminal 552 residues of mutant huntingtin (Htt-552). METHODS: Methods: Primary astrocyte cultures were prepared from the cortex of postnatal rat pups. An astrocytes model of Huntington's di...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4077128/ https://ncbi.nlm.nih.gov/pubmed/22266730 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2011.162 |
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