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Determinants of ligand selectivity in a cyclic nucleotide–regulated potassium channel
Cyclic nucleotide–binding (CNB) domains regulate the activity of channels, kinases, exchange factors, and transcription factors. These proteins are highly variable in their ligand selectivity; some are highly selective for either cAMP or cGMP, whereas others are not. Several molecular determinants o...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4076524/ https://ncbi.nlm.nih.gov/pubmed/24981229 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201311145 |
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