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Gating of the MlotiK1 potassium channel involves large rearrangements of the cyclic nucleotide-binding domains

Cyclic nucleotide-regulated ion channels are present in bacteria, plants, vertebrates, and humans. In higher organisms, they are closely involved in signaling networks of vision and olfaction. Binding of cAMP or cGMP favors the activation of these ion channels. Despite a wealth of structural and stu...

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Autores principales: Mari, Stefania A., Pessoa, João, Altieri, Stephen, Hensen, Ulf, Thomas, Lise, Morais-Cabral, João H., Müller, Daniel J.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3251111/
https://ncbi.nlm.nih.gov/pubmed/22135457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1111149108
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