A nonequilibrium binary elements-based kinetic model for benzodiazepine regulation of GABA(A) receptors

Ion channels, like many other proteins, are composed of multiple structural domains. A stimulus that impinges on one domain, such as binding of a ligand to its recognition site, can influence the activity of another domain, such as a transmembrane channel gate, through interdomain interactions. Kine...

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Main Authors: Goldschen-Ohm, Marcel P., Haroldson, Alexander, Jones, Mathew V., Pearce, Robert A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: The Rockefeller University Press 2014
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Research Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4076519/
https://ncbi.nlm.nih.gov/pubmed/24981228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201411183
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