Evidence for phosphatidylinositol 3-kinase as a regulator of endocytosis via activation of Rab5.

Phosphatidylinositol (PI) 3-kinases have been implicated in several aspects of intracellular membrane trafficking, although a detailed mechanism is yet to be established. In this study we demonstrated that wortmannin, a specific inhibitor of PI 3-kinases, inhibited constitutive endocytosis of horser...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Li, G, D'Souza-Schorey, C, Barbieri, M A, Roberts, R L, Klippel, A, Williams, L T, Stahl, P D
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1995
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40765/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7479754/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.22.10207
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